Roxithromycin was introduced by Roussel Uclaf in 1987. This antibiotic has the same 14-membered lactone ring as erythromycin. It can be purchased under several brand names. Currently, it is not available for sale in the USA, but it can be purchased in Israel, Australia and New Zealand. This medication is available in tablets or oral suspension.
Roxithromycin is an antibiotic that can be prescribed for treatment of different urinary, respiratory tract and soft tissue infections. It can be used to manage the following health conditions:
Unspecified non-gonococcal urethritis;
Hepatic function abnormal;
Lower respiratory tract infection;
Upper respiratory tract infection.
This medication is able to prevent bacteria from growing by impacting its protein synthesis. Although Roxithromycin is derived from erythromycin, it is considered to be more effective in treatment of some infections caused by gram-negative bacteria, for instance, Legionella pneumophila.
Currently, this medication undergoes certain clinical trials aimed at determining its effectiveness in treatment of male-pattern hair loss.
What Precautions Should Be Taken into Consideration?
You should not take this medication if it causes an allergic reaction or if you have a history of allergy to macrolide antibiotics. Before you are prescribed with Roxithromycin, you should tell your healthcare provider if you have porphyria or liver diseases. Also, you should provide full information about any other drugs that you may use, especially ergot-derived drugs.
What Side Effects May Occur?
When taking Roxithromycin, you may experience the following side effects:
Symptoms of pancreatitis;
Disturbances in smell or taste.
Most common side effects are gastrointestinal, but in case severe side effects occur, you should be looking for professional medical help immediately.
Can Roxithromycin Interact with Other Medications?
Roxithromycin is able to interact with different medications. It can be used along with prednisolone, hormonal contraceptives, ranitidine, carbamazepine or antacids. This medication should not be used along with warfarin sodium, midazolam, simvastatin, cyclosporine, digoxin, acenocoumarol, cabergoline and theophylline, because this will increase the effects of both medications.
Do not take Roxithromycin along with amiodarone in order to avoid additive toxicity. Remember that before you start taking Roxithromycin with other medications, you should consult your healthcare provider.